Molecular Devices - FLIPR Penta
by Molecular Devices
Molecular Devices - FLIPR Penta
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DESCRIPTION
Cellular Screening System
Powered by a new, optional high-speed EMCCD camera and the new Peak Pro 2 software module, the new FLIPR® Penta High-Throughput Cellular Screening System allows you to measure and analyze peaks of human-derived induced pluripotent stem cells (hiPSCs), differentiated into cardiomyocytes and neurons, up to 100 times per second and quickly cherry pick events such as Early Afterdepolarization-like events (EAD-like events), fibrillation, and irregular beating.
Since its introduction, the system has developed a reputation for reliability and ease of use. The system can be configured based on library size, detection mode, screening format, assay, and target, making the transition from assay development to lead optimization a seamless process.
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FEATURES
Complex event analysis
- ScreenWorks Peak Pro 2 software analysis, powered by pCLAMP 11, gives you the unique ability to characterize calcium oscillation peak data in one software program. Compounds can be flagged that cause waveform irregularities that may indicate hazards for arrhythmia, seizures, or other toxicity effects quickly and without having to export data. Distinctly different calcium oscillations in neurons can also be characterized.
Configurable optics
- The FLIPR Penta system can be matched to user needs starting with a standard EMCCD camera, a more cost-effective solution that is perfect for GPCR and Membrane Potential assays, or with the new HS EMCCD that can capture up to 100 images per second and offers exceptional luminescence performance. The camera, LEDs, and filters can be configured at the time of purchase or later when assay needs change.
User-changeable pipette modules
- Pipette heads can be changed in minutes without the use of tools from 96, 384, or 1536 channels to accommodate assay throughput needs.
Ease of use
- ScreenWorks software seamlessly incorporates drag-and-drop protocols, intuitive buttons, and color-coded plate layout to simplify workflows. View signal traces, EC50 curves, and Z factors on-the-fly without having to export data to another software program.
Validated solution
- Purchasing a FLIPR system from Molecular Devices assures users that they are investing in a technology that can grow with them. Hardware, software, and assay kits have been validated on the system by an industry-renowned leader with over 40 years of experience.
Custom automation options*
- The drug discovery process has shared methods, yet each project is unique. The Advanced Workflow Engineering Solutions Team offers a variety of customized services from automated compound plate delivery to fully integrated workstations with automated incubation.
Additional Specifications
Dimensions (in.)
- 39 (W) x 70 (H) x 27 (D)
Dimensions (cm)
- 99 (W) x 178 (H) x 69 (D)
Weight (approx.)
- 850 lbs. (386 kg)