Roche - Cobas Integra 400 plus
by Roche

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Clinical Chemistry Analyzer 

With the COBAS INTEGRA 400 plus, innovation means 4 on-board measurement technologies, robotic handling of reaction cuvettes and improved operator ergonomics. This supports the very broad menu and ease-of-use required for true workload consolidation, leading to efficiency gains only possible with only one analytical platform, one user interface, one reagent system and the one global supplier - Roche 

Sample selective bench top analyser for small to mid-size laboratories. Flexible system for consolidating routine workload with a capacity of 36 tests (including 4 ISE: Na+, K+, Li+, Cl-) on board and a throughput up to 400 test per hour.

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8 months ago
Roche/Hitachi Cobas Integra 400+ service manual wanted

Hello colleagues, please advice on Cobas Intergra 400+

if someone has last version( 2019 and up) of service manual with schemas & diagrams?

Waiting for your reply in private messages.

Equipment: Roche Cobas Integra 400+



9 months ago
hardware problem detected in the fluid controller

I got an error message about a hardware problem detected in the fluid controller with the message ID 14.3235.05.011.019.  Do anyone know what's happened and how to fix it?



3 years ago
hardware problem has been detected in cuvette controller Massage ID 14.3234.04.041.037
Problem in cobas integra 400 No temperature cassette and analyzer . hardware problem has been detected in cuvette controller Massage ID 14.3234.04.041.037 Reply


  • Faster turn around of all tests 
  • State of art performance 
  • Cost efficiency 
  • Real Security of result with the COBAS INTEGRA clot detection system 
  • INTEGRA reagent cassettes make reagent preparation a task of the past 
  • Sophisticated software programs to simplify operation and training 
  • Reduced costs through increased efficiency
  • Continuous sample access to up to 90 samples for a smoother workflow


Height75 cm
Throughput400 tests/hour
Wavelength Range340 to 800 nm
Length 66 cm
Weight230 kg
Sample Volume2 to 50 µL
Measuring Range0 to 2
Width135 cm

Additional Specifications

  • Cycle time: 10.6sec (COBAS INTEGRA 800 6sec) 
  • Reaction volumes (µl):120-245
  • Measurement range (FP): 0500mP
  • Sample: Sample Types Serum, Plasma, Urine, CSF, Hemolysate and Whole Blood (HbA1c)

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