Microm - HM520/HM525
by Microm

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DESCRIPTION
HM 520 / HM 525 Routine cryostat

The cryostat HM 520 / HM 525 combines a maximum of user benefit with highest operator comfort. Again we dedicated our special attention to the operator comfort of this Microm cryostat resulting in ergonomically shaped surfaces and intuitively comprehensible operating elements. The introduction of the stepping motor technique into this instrument class now allows reproducible as well as excellent sectioning results also in the histological/pathological routine. The Microm HM 520 Cryostat is ergonomically designed to provide excellent performance and versatility. The Microm HM 520 Cryostat will provide consistent reproducibility in the preparation of frozen sections in clinical histology laboratories requiring economical dependable performance. Microm HM 520 Cryostat is completely manual with a wheel controlled coarse feed. The HM 520 features electronic temperature control down to -35°C, fast freezing device with peltier down to -55°C and a spacious, easy to clean cooling chamber.

FORUMSView All (7)
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8

Replies
-FV
Sat Nov 29 2025
Defrost cycling causing condensation inside chamber and then causes ice buildup

Hi,

We have recently noticed ice building up on the knife holder and carrier to the point that sometimes you cannot adjust the angle of the carrier or the forward and lateral movement.  We have also seen frozen ice droplets in the chamber.  We defrosted the cryostat but the problem persists.  We then watched the defrost cycle and noticed that the chamber gets very warm and a lot of condensation occurs on the window and inside the chamber.  The display shows H - 42, which I believe indicates the temperature of the evaporator. Once the defrost cycle ends there is still a lot of condensation in the chamber and this appears to be reason we see freezing once the cryostat cools down.  Any ideas on why this happens and how to fix it are appreciated.  This started about a month ago and has never happened during the past 12 years that we have used the cryostat.  Thanks..

Equipment: Microm HM-525m Cryostat

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2

Replies
-Sheltie
Sat Feb 01 2025
Icing up.

Knife/blade holder block keeps icing up but the chamber, frozen section sample holder and cutting block do not ice up. The sample freezes appropriately.  Why does the knife/blade block ice up?  Solution?

Equipment: Thermo Shandon HM525 NX UV

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1

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-Sheltie
Sat Feb 01 2025
Ice formation

Ice forms on the block that holds the cutting blade.  The rest of the chamber and all equipment (incuding peg/chuck holder) remain ice free.  Any ideas on why this happens and how to fix it are appreciated.


Equipment: Thermo Shandon Cryostat HM525 NX UV

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DOCUMENTS / MANUALSView All

FEATURES

[list]    [*] Ergonomically Designed    [*] Excellent performance and    [*] Motorized coarse feed for rapid trimming    [*] Trim from 1 to 60 um with a 59mm vertical stroke    [*] 25 mm horizontal specimen feed    [*] set from a range of 0°C to -35°C    [*] Shelf that cools to -45°C.    [*] Battery backup parameters    [/list]

SPECIFICATIONS

Height47 in
Length 30 in
Weight315 lbs
Width25 in
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